套件：melting（5.2.0-2）

compute the melting temperature of nucleic acid duplex

This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough.

標籤: 領域: 生物學, 生物資訊學, field::biology:molecular, implemented-in::c, 使用者介面: 命令行, 角色: role::program, scope::utility, 應用程式集: GNU, Purpose: use::analysing, works-with-format::plaintext, 處理: 需要一個額外的標籤

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