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[ 源代码: disulfinder  ]

软件包:disulfinder(1.2.11-8)

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cysteines disulfide bonding state and connectivity predictor

'disulfinder' is for predicting the disulfide bonding state of cysteines and their disulfide connectivity starting from sequence alone. Disulfide bridges play a major role in the stabilization of the folding process for several proteins. Prediction of disulfide bridges from sequence alone is therefore useful for the study of structural and functional properties of specific proteins. In addition, knowledge about the disulfide bonding state of cysteines may help the experimental structure determination process and may be useful in other genomic annotation tasks.

'disulfinder' predicts disulfide patterns in two computational stages: (1) the disulfide bonding state of each cysteine is predicted by a BRNN-SVM binary classifier; (2) cysteines that are known to participate in the formation of bridges are paired by a Recursive Neural Network to obtain a connectivity pattern.

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硬件架构 软件包大小 安装后大小 文件
amd64 232.3 kB650.0 kB [文件列表]
arm64 202.1 kB566.0 kB [文件列表]
armhf 190.3 kB377.0 kB [文件列表]
i386 241.2 kB673.0 kB [文件列表]