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[ Source: libvcflib  ]

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C++ library for parsing and manipulating VCF files

The Variant Call Format (VCF) is a flat-file, tab-delimited textual format intended to concisely describe reference-indexed variations between individuals. VCF provides a common interchange format for the description of variation in individuals and populations of samples, and has become the defacto standard reporting format for a wide array of genomic variant detectors.

vcflib provides methods to manipulate and interpret sequence variation as it can be described by VCF. It is both:

 * an API for parsing and operating on records of genomic variation as it can
   be described by the VCF format,
 * and a collection of command-line utilities for executing complex
   manipulations on VCF files.

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